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⚛️

Longevity Pathways

The master regulators of aging — mTOR, AMPK, sirtuins, insulin/IGF-1, and autophagy — how diet, fasting, exercise, and emerging drugs act on them.

7 lessons·~2h·1,315 XP·🏆 Certificate on completion
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Module 1The Nutrient-Sensing Network

The grow-vs-repair decision and the growth-signaling pathway.

  1. 1
    The Master Regulators
    Growth vs repair, and the four pathways
    16 min
    190
  2. 2
    Insulin & IGF-1 Signaling
    Where longevity genetics began
    15 min
    185
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Module 2Growth vs. Repair

The two opposing master switches.

  1. 1
    mTOR: The Growth Switch
    Rapamycin and the growth-vs-longevity tension
    16 min
    190
  2. 2
    AMPK: The Energy Sensor
    The repair team's captain
    15 min
    185
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Module 3Repair & Maintenance

Sirtuins, NAD+, and the control of autophagy.

  1. 1
    Sirtuins & NAD+
    The maintenance enzymes and their fuel
    16 min
    190
  2. 2
    How the Pathways Control Autophagy
    Where it all converges
    15 min
    185
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Module 4Acting on the Pathways

The behavioral and pharmacological levers, honestly.

  1. 1
    Acting on the Pathways
    Behavior, drugs, and hype vs evidence
    16 min
    190