FSK53 Kanna Extract Quick Dissolve Tablets

Why Should I Take Kanna? Sceletium tortuosum, also known as kanna, is a very unique succulent which is native to South Africa. It has been used there by the locals for hundreds of years, primarily for its potent mood boosting properties. In 1738, the German explorer Peter Kolben even noted that kanna is “the greatest chearer of the spirits, and the noblest restorative in the world”. We have to agree here with Peter Kolben because kanna is indeed one of the most unique and quick acting mood boosting botanicals we have ever come across!* That being said, there is an enormous variety in effects profiles between different kanna extracts, ranging from a warm and cozy mood boost to a cold and sterile stimulation.* Thus, we had our work cut out for us when finding the best overall kanna extract! If you’ve already tried kanna, you probably have a pretty good idea of just how fun our beta-testing was! We tested 10 different kanna extracts, all of which had very unique effects. The highly standardized extracts, which basically only contained the bioactive compound mesembrine, were very energizing but lacked some of the warm and cozy mood boosting properties that kanna can provide. Moving down into the more full spectrum extracts, we lost some of the unique energizing properties, but in return we got a lot of warm, cozy and physically relaxing effects. One day, we tried a kanna extract that blew all of us away. It provided significant energizing effects while also providing a warm mood boost and a significant physically relaxing effect. This was by far the most full spectrum feeling kanna we had tried while also being powerful, sometimes even overwhelmingly so in its effects!* This is obviously the kanna extract we ended up settling on and over the past few months it has quickly become one of our all time favorite mood boosters.* We are super excited to be able to offer this unique kanna extract now! So if you are looking for a big mood boost, look no further than our full spectrum kanna extract!* What is Kanna? Sceletium tortuosum, also known as kanna, is a succulent which is native to South Africa. Specifically, it seems to occur most commonly in the wild in the unique Succulent Karoo ecoregion. It has been used here for a very long time, specifically by hunter gatherers who use the plant for its mood boosting but also appetite suppressing and energizing effects. Traditionally, the succulent is harvested and crushed with a rock after which it is rolled up and fermented. The fermented kanna is then chewed for its effects, which is also part of the reason it is nicknamed “kauwgoed” which loosely translates to “something that is chewed”. The fermented kanna is also often sun dried and pulverized into a powder to be used as a tea or even snuff. Kanna contains a wide variety of unique bioactive compounds, many of which have not been properly explored in isolation yet. The most well studied compounds in kanna are mesembrine and mesembrenone. These compounds act as monoamine releasers, serotonin reuptake inhibitors and PDE-4 inhibitors which all contribute to the unique mood boosting properties of kanna. Another compound that is often tested for, Δ7 -mesembrenone, has not been explored much in studies in order to assess its pharmacodynamic properties, however, we have a sneaking suspicion that it is quite important for the warm and cozy effects that kanna can produce.* During our beta-testing, it was quite apparent that extracts which had higher Δ7 -mesembrenone content felt more full bodied and physically relaxing while providing a mood boost that felt more “warm”.* Kanna Benefits & Uses Boosts mood* Increases energy* Supports pain management* An Ancient Succulent Mood Booster When exploring the pharmacodynamic profile of kanna, it is exceptionally easy to see why it is such a revered mood boosting botanical.* One of the stand out effects of kanna is that it significantly upregulates the vesicular monoamine transporter 2 (VMAT-2) mainly through its mesembrine content. This transporter is crucial for the release of various neurotransmitters such as serotonin and dopamine into the synaptic cleft where these neurotransmitters can then act on their corresponding receptors. This is very different from the effects of reuptake inhibitors or monoamine oxidase inhibitors, which prevent monoamine neurotransmitter removal from the synaptic cleft (reuptake inhibitors) or their breakdown (monoamine oxidase inhibitors). In general, monoamine releasers tend to produce more significant effects while also oftentimes being quite smooth. While VMAT-2 regulates the release of all of the monoamine neurotransmitters, kanna is oftentimes seen as a serotonergic botanical. This is due to the fact that via kanna’s mesembrenone and mesembrine content, the serotonin transporter is also inhibited. This means that the serotonin which is released into the synaptic cleft via the VMAT-2 mechanism hangs around much longer than the other monoamine n