Skip to main content
Catalog/5-HTP
5-HTP — image 1 of 7

5-HTP

💊Capsule
💤Sleep😊Mood🧘Stress
🛡️NSF Certified🏭GMP📊Clinical EvidenceHigh Bioavailability💪Optimal Doses

High-quality creatine for lean muscle mass, endurance, cellular energy, and brain function* 5-HTP increases serotonin levels to promote restful sleep, manage stress, and decrease sugar cravings.* It contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.

Want to track 5-HTP?
Download Formulate free to build your stack, log daily intake, and get personalized feedback — no account required to browse scores.
Download Free

Overview

High-quality creatine for lean muscle mass, endurance, cellular energy, and brain function* 5-HTP increases serotonin levels to promote restful sleep, manage stress, and decrease sugar cravings.* It contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.

Warnings

ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY WARNING If pregnant or nursing, do not use this product. INTERACTIONS 5-HTP should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.

Active Ingredients

OPTIMALGOOD
Vitamin B6
Pyridoxal 5'-Phosphate
6.8mg
400% DV
OPTIMALHIGH BIO

Other Ingredients

Hypromellose (derived from cellulose) capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide

Product Info

Serving Size
2 Capsules
Servings
90
Price
$39.00
Per Serving
$0.43
Form
capsule

Where to Buy

Links may contain affiliate partnerships. See our disclosure for details.

Certifications

NSF CertifiedGluten FreeDairy FreeSoy FreeThorne VerifiedNatural FlavorsNatural ColorsGMP Certified

Score Breakdown

Evidence Quality
25%92
1 Grade A, 1 Grade B ingredients
Evidence grades: A(1), B(1)
1 ingredient(s) have Grade B evidence - all A's would score higher
Dose Adequacy
20%95
Optimal: 5-Hydroxytryptophan, Vitamin B6 (as Pyridoxal 5'-Phosphate)
Reference coverage: 100%
Form/Bioavailability
20%94
1 high bioavailability: Vitamin B6 (Pyridoxal 5'-Phosphate)
1 good: 5-Hydroxytryptophan (standard)
Excellent form quality - premium bioavailable forms
Transparency
10%100
Full disclosure - all doses labeled
Safety/Redundancy
10%83
DANGER: 5_htp + SSRIs/SNRIs — Serotonin syndrome risk (agitation, tremor, hyperthermia, ta
DANGER: 5_htp + MAOIs — Severe serotonin syndrome - potentially fatal
Drug interactions: SSRIs, MAOIs, triptans - serious interaction, Triptans (migraine) (Serotonin syndrome risk)
Contraindications: SSRIs, MAOIs, Carcinoid tumors
Focused formula (2 ingredients)
May interact with: SSRIs, MAOIs, triptans - serious interaction, Triptans (migraine) (Serotonin syndrome risk)
Consult healthcare provider if taking medications
Review if you have: SSRIs, MAOIs, Carcinoid tumors
Manufacturing Quality
10%80
Third-party testing verified
Certifications: Third-party tested, NSF Certified, GMP Certified
NSF Certified for Sport offers even stricter testing standards
Missing: NSF Certified for Sport, USP Verified
Overall Score90/100

Related Resources