Catalog/Methyl-Guard Plus

Methyl-Guard Plus

Name: Methyl-Guard Plus
Brand: Thorne
Price: 62.00 USD
Availability: InStock

ThorneA-

💊Capsule

❤️Heart Health🧬Methylation

🏭GMP📊Clinical Evidence⭐High Bioavailability💪Optimal Doses

Support cellular energy production, heart health, brain function, and mood with nutrients that optimize methylation* Methyl-Guard Plus provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.*

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Overview

Warnings

ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY: If pregnant, consult your health-care practitioner before using this product. INTERACTIONS: 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity. however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

Active Ingredients

Betaine Anhydrous↗

Trimethylglycine

1.8g

55% TR

OPTIMALHIGH BIO

Vitamin B12↗

Methylcobalamin

3mg

125000% DV

OPTIMALHIGH BIO

Riboflavin↗

Riboflavin 5'-Phosphate Sodium

90mg

6923% DV

OPTIMALGOOD

Vitamin B6↗

Pyridoxal 5'-Phosphate

45mg

2647% DV

OPTIMALHIGH BIO

Folate↗

3 mg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt

5mg

1250% DV

OPTIMALGOOD

Other Ingredients

Calcium Citrate, Calcium Laurate, Hypromellose (derived from cellulose) capsule

Product Info

Serving Size

Three Capsules

Servings

Price

$62.00

Per Serving

$2.07

Form

capsule

Where to Buy

Official Website Amazon iHerb

Links may contain affiliate partnerships. See our disclosure for details.

Certifications

Gluten FreeSoy FreeDairy FreeDerived From Natural FlavorsDerived From Natural ColorsMade in USAThorne VerifiedGMP

Score Breakdown

Evidence Quality

25%97

•4 Grade A, 1 Grade B ingredients

•Evidence grades: A(4), B(1)

•1 ingredient(s) have Grade B evidence - all A's would score higher

Dose Adequacy

20%90

•Optimal: Riboflavin (as Riboflavin 5'-Phosphate Sodium), Vitamin B6 (as Pyridoxal 5'-Phosphate), Folate (3 mg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt), Vitamin B12 (as Methylcobalamin), Betaine Anhydrous (Trimethylglycine)

•Reference coverage: 100%

•Caution: Folate (3 mg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) near upper limit (1000 mg/day)

•Folate (3 mg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt): Use methylfolate instead; ensure adequate B12 status

Form/Bioavailability

20%92

•3 high bioavailability: Vitamin B6 (Pyridoxal 5'-Phosphate), Vitamin B12 (Methylcobalamin), Betaine Anhydrous (standard)

•1 good: Riboflavin (Riboflavin 5'-Phosphate Sodium)

•1 basic

•Excellent form quality - premium bioavailable forms

•Consider Folate as methylfolate (5-MTHF) instead of L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt

•Primary ingredient Riboflavin could use a higher bioavailability form

Transparency

10%100

•Full disclosure - all doses labeled

Safety/Redundancy