Bifidobacterium longum
Probiotic
Also known as: B. longum, B. longum 1714, Bifido
B
Grade B💊 1-10 billion CFU daily🎯 4 primary uses🔗 2 synergies⚠️ Review warnings
Levels upNutrition+50 pts
Overview
Dominant infant gut bacteria that supports immune function and may reduce anxiety. Important throughout life.
Primary Uses
Immune supportAnxiety/moodGut healthInflammation
Frequently Asked About Bifidobacterium longum
How much Bifidobacterium longum should I take?
The typical effective range is 1-10 billion CFU daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Bifidobacterium longum?
Any time. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Bifidobacterium longum with food?
Either way.
Does Bifidobacterium longum interact with medications?
Yes — known interactions include Standard probiotic. If you take any prescription medication, talk to your doctor or pharmacist before starting Bifidobacterium longum.
What does Bifidobacterium longum pair well with?
Bifidobacterium longum stacks well with GOS prebiotic and Other Bifidobacteria — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Bifidobacterium longum?
Bifidobacterium longum should be avoided or used with caution by people with Severe immunocompromise. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Bifidobacterium longum?
Most people tolerate Bifidobacterium longum well. The most commonly reported side effects are Minimal. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
1-10 billion CFU daily
Timing
Any time
With food
Either way
Duration
Safe long-term
Special Populations
Stress, immune support
Research & Studies
Search the literature now
We haven’t curated landmark studies for Bifidobacterium longumyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Search Bifidobacterium longum research
Mechanism of Action
- • Immune modulation
- • GABA production
- • Anti-inflammatory
Evidence Quality
Evidence Grade B
Important from infancy through aging
Safety & Contraindications
Serious Warnings
- • Standard cautions
Contraindications
- • Severe immunocompromise
Common Side Effects
- • Minimal
Pregnancy & Breastfeeding
Consult healthcare provider
Liver & Kidney Notes
Safe
Interactions
💊 Medications
- • Standard probiotic
🧪 Supplements
- • Works with prebiotics (especially GOS)
🍽️ Food & Alcohol
- • No interactions
Stacking & Synergies
Pairs Well With
GOS prebiotic ↗Other Bifidobacteria
Avoid Combining With
None
Best Goal Synergies
ImmuneMood
Buying Guide
What to Look For
- • Specific strain
Standardization Markers
CFU count
Adulteration risk
Low
Practical Notes
- • Important for gut-brain axis
- • Decreases with age
Tags
probioticgut healthimmunemood
Related Guides
In-depth guides covering Bifidobacterium longum — protocols, comparisons, and use cases.
More in Probiotic
Other ingredients in the Probiotic category.
Bifidobacterium breve
A probiotic strain commonly found in the infant gut microbiome, supporting digestive health, immune function, and skin health.
Bifidobacterium infantis 35624
Most-studied probiotic strain for IBS. Repeated RCTs show symptom improvement at 1 billion CFU/day.
Bifidobacterium lactis
Hardy probiotic strain with strong immune-enhancing effects. Survives transit well and supports regularity.
Lacticaseibacillus casei
A well-researched probiotic strain supporting digestive health, immune function, and overall gut microbiome balance.
Lactobacillus acidophilus
Foundational probiotic strain for vaginal and gut health. One of the most studied probiotic species.
Lactobacillus plantarum
Versatile probiotic with gut barrier support and anti-inflammatory effects. Found in fermented vegetables.
Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Bifidobacterium longum — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/bifidobacterium-longum
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.