Lacticaseibacillus casei

Probiotic

Also known as: Lactobacillus casei, L. casei, Lacticasei casei

Grade A

💊 1-20 billion CFU daily🎯 4 primary uses✅ Generally safe

Compare Check interactions

Levels upNutrition+50 pts

Overview

A well-researched probiotic strain supporting digestive health, immune function, and overall gut microbiome balance.

Primary Uses

Digestive healthImmune supportGut microbiome balanceDiarrhea prevention

Frequently Asked About Lacticaseibacillus casei

How much Lacticaseibacillus casei should I take?

The typical effective range is 1-20 billion CFU daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.

When is the best time to take Lacticaseibacillus casei?

Any time. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.

Should I take Lacticaseibacillus casei with food?

Optional.

What are the side effects of Lacticaseibacillus casei?

Most people tolerate Lacticaseibacillus casei well. The most commonly reported side effects are Mild gas initially. Side effects are usually dose-dependent — lowering the dose often resolves them.

Dosage

Typical range

1-20 billion CFU daily

Timing

Any time

With food

Optional

Duration

Safe for ongoing daily use

Special Populations

Studied across all age groups including pediatric

Research & Studies

Search the literature now

We haven’t curated landmark studies for Lacticaseibacillus caseiyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.

Search Lacticaseibacillus casei research

PubMed (RCTs) ↗Randomized trials PubMed (all) ↗Full literature Cochrane Reviews ↗Systematic reviews Examine.com ↗Research summaries

Browse all curated studies →

Mechanism of Action

• Colonizes intestinal mucosa
• Produces lactic acid lowering gut pH
• Competes with pathogenic bacteria
• Stimulates immune responses

Evidence Quality

Evidence Grade A

Extensive clinical research including large RCTs

Safety & Contraindications

Common Side Effects

• Mild gas initially

Pregnancy & Breastfeeding

Consult healthcare provider

Interactions

🧪 Supplements

• Synergistic with other probiotics and prebiotics

Buying Guide

Standardization Markers

CFU countStrain identification

More in Probiotic

Other ingredients in the Probiotic category.

Bifidobacterium breve

A probiotic strain commonly found in the infant gut microbiome, supporting digestive health, immune function, and skin health.

Bifidobacterium infantis 35624

Most-studied probiotic strain for IBS. Repeated RCTs show symptom improvement at 1 billion CFU/day.

Bifidobacterium lactis

Hardy probiotic strain with strong immune-enhancing effects. Survives transit well and supports regularity.

Bifidobacterium longum

Dominant infant gut bacteria that supports immune function and may reduce anxiety. Important throughout life.

Lactobacillus acidophilus

Foundational probiotic strain for vaginal and gut health. One of the most studied probiotic species.

Lactobacillus plantarum

Versatile probiotic with gut barrier support and anti-inflammatory effects. Found in fermented vegetables.

Browse all Probiotic ingredients →

Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.

Cite this page

Formulate Research Team. (2026, June). Lacticaseibacillus casei — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/lacticaseibacillus-casei

Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.