Nefiracetam
Nootropic
Also known as: DM-9384
C
Grade C💊 400-800 mg daily divided🎯 4 primary uses🔗 2 synergies⚠️ Review warnings
Overview
Fat-soluble racetam with unique GABAergic effects. Enhances long-term potentiation.
Primary Uses
MemoryMoodNeuroprotectionApathy
Dosage
Typical range
400-800 mg daily divided
Timing
With fatty meals
With food
Yes, essential
Duration
Cumulative benefits
Special Populations
Memory, apathy
Mechanism of Action
- • Enhances GABAergic signaling
- • Calcium channel modulation
- • Long-term potentiation enhancement
Evidence Quality
Evidence Grade C
Unique GABAergic racetam
Safety & Contraindications
Serious Warnings
- • Testicular toxicity in dogs (not humans)
Contraindications
- • Unknown
Common Side Effects
- • Headache
- • GI upset
Pregnancy & Breastfeeding
Avoid
Liver & Kidney Notes
Monitor
Interactions
💊 Medications
- • GABAergic drugs
🧪 Supplements
- • Choline helpful
🍽️ Food & Alcohol
- • Take with fat
Stacking & Synergies
Pairs Well With
Alpha-GPCFat source
Avoid Combining With
Unknown
Best Goal Synergies
MemoryApathy
Buying Guide
What to Look For
- • Lab-tested
Standardization Markers
Purity
Adulteration risk
Moderate
Practical Notes
- • Take with fat
- • Dog toxicity not seen in humans
Tags
nootropicracetamGABAergicmemory
Frequently Asked About Nefiracetam
How much Nefiracetam should I take?
The typical effective range is 400-800 mg daily divided. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Nefiracetam?
With fatty meals. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Nefiracetam with food?
Yes, essential.
Does Nefiracetam interact with medications?
Yes — known interactions include GABAergic drugs. If you take any prescription medication, talk to your doctor or pharmacist before starting Nefiracetam.
What does Nefiracetam pair well with?
Nefiracetam stacks well with Alpha-GPC and Fat source — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Nefiracetam?
Nefiracetam should be avoided or used with caution by people with Unknown. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Nefiracetam?
Most people tolerate Nefiracetam well. The most commonly reported side effects are Headache and GI upset. Side effects are usually dose-dependent — lowering the dose often resolves them.
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.