Progesterone Cream (Bio-identical)
Hormone
Also known as: Bio-identical progesterone, Micronized progesterone cream, Progest
B
Grade B💊 Varies - OTC 20-40mg/application, Rx as prescribed🎯 3 primary uses🔗 1 synergy⚠️ Review warnings
Overview
Actual progesterone in cream form, requires practitioner guidance for hormone therapy.
Primary Uses
Progesterone supplementationLuteal phase supportMenopause
Dosage
Typical range
Varies - OTC 20-40mg/application, Rx as prescribed
Timing
Often luteal phase days 14-28
With food
N/A (topical)
Duration
Per practitioner guidance
Special Populations
Women with low progesterone, luteal phase defect, menopause
Mechanism of Action
- • Delivers actual progesterone
- • Transdermal absorption
- • Supports luteal phase
- • Menopause hormone therapy
Evidence Quality
Evidence Grade B
Effective for progesterone delivery when properly prescribed
Safety & Contraindications
Serious Warnings
- • This is hormone therapy
- • Requires proper assessment
- • Not DIY
Contraindications
- • Breast cancer history
- • Liver disease
- • Undiagnosed bleeding
Common Side Effects
- • Skin irritation
- • Drowsiness
- • Mood changes
Pregnancy & Breastfeeding
Used in some pregnancy support protocols - Rx only
Liver & Kidney Notes
Transdermal bypasses first-pass liver
Interactions
💊 Medications
- • HRT (coordinate)
- • May affect other hormones
🧪 Supplements
- • Not herbs that contain diosgenin
🍽️ Food & Alcohol
- • N/A
Stacking & Synergies
Pairs Well With
Comprehensive hormone therapy if prescribed
Avoid Combining With
Self-prescribing without testing
Best Goal Synergies
Actual progesterone supplementation
Buying Guide
What to Look For
- • USP grade progesterone
- • Proper dosing information
- • Preferably Rx
Standardization Markers
USP progesteroneMg per application
Adulteration risk
Low if pharmaceutical grade
Practical Notes
- • This is real hormone therapy
- • Get hormone levels tested
- • Work with knowledgeable practitioner
Tags
hormoneprogesteronebio-identicalprescription
Frequently Asked About Progesterone Cream (Bio-identical)
How much Progesterone Cream (Bio-identical) should I take?
The typical effective range is Varies - OTC 20-40mg/application, Rx as prescribed. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Progesterone Cream (Bio-identical)?
Often luteal phase days 14-28. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Progesterone Cream (Bio-identical) with food?
N/A (topical).
Does Progesterone Cream (Bio-identical) interact with medications?
Yes — known interactions include HRT (coordinate) and May affect other hormones. If you take any prescription medication, talk to your doctor or pharmacist before starting Progesterone Cream (Bio-identical).
What does Progesterone Cream (Bio-identical) pair well with?
Progesterone Cream (Bio-identical) stacks well with Comprehensive hormone therapy if prescribed — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Progesterone Cream (Bio-identical)?
Progesterone Cream (Bio-identical) should be avoided or used with caution by people with Breast cancer history, Liver disease, and Undiagnosed bleeding. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Progesterone Cream (Bio-identical)?
Most people tolerate Progesterone Cream (Bio-identical) well. The most commonly reported side effects are Skin irritation, Drowsiness, and Mood changes. Side effects are usually dose-dependent — lowering the dose often resolves them.
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.