#6 of 138 in Vegetable · scored 96/100
Also known as broccoli florets, broccolini
Broccoli is a cruciferous vegetable rich in vitamin C, vitamin K, and sulforaphane, a potent bioactive compound with anti-inflammatory and detoxification properties. Its dense nutrient profile and low calorie content make it a longevity staple.
3.4 g net carbs after fiber.
Representative amounts for this food, not measured for this item. Real content varies widely by variety, ripeness and storage.
These are the scored components, not a sum: the published score also reflects normalisation across the catalog, so the parts above will not add to 96.
Less a 2.0 anti-nutrient penalty (high sodium).
Broccoli (Brassica oleracea var. italica) originated in the Mediterranean region and has been cultivated for over 2,000 years. As a cruciferous vegetable, it contains glucosinolates—compounds that convert to isothiocyanates like sulforaphane when cells are damaged during chewing or cooking. Per 100g, broccoli delivers 101.6 mcg of vitamin K (essential for bone mineralization and vascular health), 89.2 mg of vitamin C (supporting immune function and collagen synthesis), and 2.6g of fiber (promoting gut microbiota diversity). The sulforaphane content is particularly relevant for longevity research, with studies showing activation of Nrf2 pathways that enhance cellular defense against oxidative stress and support Phase II detoxification enzymes. Broccoli's high potassium-to-calorie ratio aids cardiovascular regulation, while its folate content supports methylation and neurological health. Regular consumption has been associated with reduced risk of chronic diseases including certain cancers, cardiovascular disease, and cognitive decline. The vegetable's anti-inflammatory properties make it valuable for aging populations seeking to reduce systemic inflammation, a key hallmark of aging.
Sulforaphane activates NRF2 transcription factor, upregulating antioxidant response elements and Phase II detoxification enzymes (glutathione-S-transferases, NAD(P)H quinone oxidoreductase) that neutralize free radicals and eliminate xenobiotics
Vitamin K (101.6 mcg/100g) serves as a cofactor for osteocalcin and matrix Gla protein (MGP), directing calcium to bone matrix and away from arterial walls, reducing fracture risk and arterial stiffness
Sulforaphane inhibits NF-κB signaling pathways and reduces pro-inflammatory cytokine production (TNF-α, IL-6), while vitamin C supports immune cell proliferation and pathogen clearance
High potassium (316 mg/100g) supports sodium-potassium ATPase function for vascular relaxation; sulforaphane may improve endothelial function and reduce atherosclerotic plaque formation via anti-inflammatory mechanisms
Isothiocyanates from glucosinolates induce phase II detoxification enzymes, promote apoptosis in pre-malignant cells, and inhibit angiogenesis; fiber supports favorable gut microbiota composition and short-chain fatty acid production
Broccoli contains no bioactive compounds timing-dependent for absorption or efficacy. Its fiber may slightly delay gastric emptying, making it suitable with any meal. Consuming at lunch or dinner with fat-containing foods (olive oil, fish, nuts) optimizes fat-soluble vitamin K absorption. No specific pre/post-workout advantage.
Breaks a fast
While broccoli is compatible with intermittent fasting windows, its fiber and volume make it more satiating with meals. Those with thyroid dysfunction on levothyroxine should maintain consistent intake rather than clustering consumption on specific days.