Vascular NO
eNOS → nitric oxide, vasodilation, endothelial function
This is the chemistry of keeping blood vessels open and responsive. The endothelium — the lining of every vessel — makes nitric oxide from the amino acid L-arginine via the enzyme eNOS; nitric oxide signals the vessel wall to relax and widen, lowering blood pressure and improving blood flow. L-citrulline recycles back into arginine to keep the supply up, vitamin C protects nitric oxide from being destroyed by oxidative stress, and omega-3 + magnesium support endothelial tone. Endothelial dysfunction — losing this nitric-oxide capacity — is one of the earliest measurable steps toward cardiovascular disease, often decades before symptoms.
How your supplements + diet feed this pathway right now — the cofactors driving it, where the gaps are, and your own lab readouts.
The load-bearing nutrients — if these are deficient, this pathway slows down. Click any to see daily targets, food sources, and supplements that supply it.
Nutrients that contribute to this pathway but aren’t the single load-bearing inputs.
Lab markers that report on how well this pathway is running. When one of these is out of range, this pathway is often where the upstream issue lives.
Save a lab session under My Journey → Biomarkers to see your own values for these.
Pathways that share a load-bearing cofactor with this one.