Andrographis

Immune Support

Also known as: Andrographis paniculata, King of Bitters, Kalmegh, Andrographis (Andrographis paniculata), Andrographis Extract

Grade A

💊 200-400mg standardized extract daily🎯 9 primary uses🔗 3 synergies⚠️ Review warnings

Overview

Andrographis paniculata is a traditional Ayurvedic and Southeast Asian herb containing andrographolide as its primary bioactive compound. Research suggests potential immune-supporting and anti-inflammatory properties, though evidence in humans remains moderate.

Primary Uses

Cold/flu treatmentSore throatFever reductionImmune supportUpper respiratoryAnti-inflammatoryCold and flu symptom managementAnti-inflammatory supportRespiratory health

Dosage

Typical range

200-400mg standardized extract daily

Timing

With meals

With food

Yes, reduces GI upset

Duration

Short-term for acute illness, cycle for maintenance

Special Populations

Acute infections, immune support

Mechanism of Action

• Immune cell activation
• NF-kB inhibition
• Antipyretic effects
• Antiviral properties

Evidence Quality

Evidence Grade A

Strong clinical evidence for upper respiratory infections

Safety & Contraindications

Serious Warnings

• May affect fertility
• Hypotension possible

Contraindications

• Pregnancy
• Autoimmune conditions
• Low blood pressure

Common Side Effects

• GI upset
• Fatigue
• Headache
• Bitter taste

Pregnancy & Breastfeeding

Avoid - may affect fertility/pregnancy

Liver & Kidney Notes

Generally safe, monitor with liver conditions

Interactions

💊 Medications

• Blood thinners
• Blood pressure medications
• Immunosuppressants

🧪 Supplements

• Works with echinacea, elderberry

🍽️ Food & Alcohol

• With meals

Stacking & Synergies

Pairs Well With

EchinaceaElderberryVitamin C

Avoid Combining With

ImmunosuppressantsBlood thinners without monitoring

Best Goal Synergies

Immune supportCold/flu

Buying Guide

What to Look For

• Standardized to andrographolides
• Third-party tested

Standardization Markers

Andrographolide content (10-30%)

Adulteration risk

Low

Practical Notes

• Very bitter - capsules preferred
• Start at first symptom
• Not for long-term use
• Standardized extract important
• Not for long-term continuous use

Frequently Asked About Andrographis

How much Andrographis should I take?

The typical effective range is 200-400mg standardized extract daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.

When is the best time to take Andrographis?

With meals. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.

Should I take Andrographis with food?

Yes, reduces GI upset.

Does Andrographis interact with medications?

Yes — known interactions include Blood thinners, Blood pressure medications, and Immunosuppressants. If you take any prescription medication, talk to your doctor or pharmacist before starting Andrographis.

What does Andrographis pair well with?

Andrographis stacks well with Echinacea, Elderberry, and Vitamin C — these combinations either improve absorption or work synergistically toward common goals.

Who should not take Andrographis?

Andrographis should be avoided or used with caution by people with Pregnancy, Autoimmune conditions, and Low blood pressure. Pregnant or breastfeeding women should consult a healthcare provider before use.

What are the side effects of Andrographis?

Most people tolerate Andrographis well. The most commonly reported side effects are GI upset, Fatigue, and Headache. Side effects are usually dose-dependent — lowering the dose often resolves them.

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Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.