#1 of 138 in Vegetable · scored 98/100
Also known as brussels sprout
Brussels sprouts are cruciferous vegetables rich in vitamin K, vitamin C, and sulfur-containing compounds called glucosinolates that support detoxification and cellular health.
4.4 g net carbs after fiber.
Representative amounts for this food, not measured for this item. Real content varies widely by variety, ripeness and storage.
These are the scored components, not a sum: the published score also reflects normalisation across the catalog, so the parts above will not add to 98.
Brussels sprouts are small, cabbage-like vegetables native to Belgium that have gained prominence in longevity nutrition due to their exceptional micronutrient density and bioactive compound profile. Per 100g, they deliver 177 mcg of vitamin K (essential for bone mineralization and vascular health), 62 mg of vitamin C (supporting immune function and collagen synthesis), and substantial folate for methylation and DNA repair. Their unique selling point is the glucosinolate content—sulfur compounds that convert to sulforaphane and indole-3-carbinol (I3C) upon chewing or cooking. These compounds activate phase II detoxification enzymes in the liver, potentially reducing carcinogenic metabolite accumulation. The 3.8g of fiber per serving supports healthy gut microbiota composition, which correlates with improved metabolic health, reduced inflammation markers, and enhanced longevity outcomes. Brussels sprouts also provide kaempferol, a flavonoid with demonstrated anti-inflammatory and neuroprotective properties. Their low glycemic load (9g carbs, high fiber ratio) makes them suitable for metabolic health optimization across various dietary patterns. Regular consumption has been associated with reduced cancer risk in observational studies, particularly for colorectal and breast cancers in populations with adequate intake.
Glucosinolates convert to sulforaphane and indole-3-carbinol, which activate cytochrome P450 and phase II detoxification enzymes (glutathione S-transferases, UDP-glucuronosyltransferases), improving xenobiotic elimination
High vitamin K content activates osteocalcin and matrix Gla-protein, proteins critical for bone mineralization and preventing arterial calcification
Kaempferol and other flavonoids inhibit NF-κB signaling and pro-inflammatory cytokine production, while vitamin C supports antioxidant defenses
Insoluble and soluble fiber promotes growth of SCFA-producing bacteria (Faecalibacterium prausnitzii, Roseburia spp.), reducing lipopolysaccharide translocation and systemic inflammation
Folate (60 mcg/100g) acts as a methyl donor in homocysteine remethylation, reducing cardiovascular disease risk associated with elevated homocysteine
Brussels sprouts have no time-dependent bioavailability considerations; their fiber, vitamins, and phytonutrients are equally effective throughout the day. Including them at lunch or dinner promotes satiety and stable blood glucose due to high fiber content.
Breaks a fast
While not fasting-compatible due to caloric content, they're optimal for breaking fasts with complex nutrition density without glycemic disruption.