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Avocado-Soy Unsaponifiables (ASU)

Joint Health

Also known as: ASU, Piascledine

B
Grade B
💊 300mg daily🎯 3 primary uses🔗 3 synergies⚠️ Review warnings

Overview

Lipid extract that may protect cartilage and reduce need for NSAIDs in osteoarthritis.

Primary Uses
Cartilage protectionOsteoarthritisJoint health

Frequently Asked About Avocado-Soy Unsaponifiables (ASU)

How much Avocado-Soy Unsaponifiables (ASU) should I take?
The typical effective range is 300mg daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Avocado-Soy Unsaponifiables (ASU)?
With food. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Avocado-Soy Unsaponifiables (ASU) with food?
Yes.
Does Avocado-Soy Unsaponifiables (ASU) interact with medications?
Yes — known interactions include None significant. If you take any prescription medication, talk to your doctor or pharmacist before starting Avocado-Soy Unsaponifiables (ASU).
What does Avocado-Soy Unsaponifiables (ASU) pair well with?
Avocado-Soy Unsaponifiables (ASU) stacks well with Glucosamine, Chondroitin, and Boswellia — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Avocado-Soy Unsaponifiables (ASU)?
Avocado-Soy Unsaponifiables (ASU) should be avoided or used with caution by people with Soy allergy. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Avocado-Soy Unsaponifiables (ASU)?
Most people tolerate Avocado-Soy Unsaponifiables (ASU) well. The most commonly reported side effects are GI upset. Side effects are usually dose-dependent — lowering the dose often resolves them.

Dosage

Typical range
300mg daily
Timing
With food
With food
Yes
Duration

3+ months for effects

Special Populations

Osteoarthritis, cartilage protection

Research & Studies

Search the literature now

We haven’t curated landmark studies for Avocado-Soy Unsaponifiables (ASU)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.

Browse all curated studies →

Mechanism of Action

  • May inhibit cartilage breakdown
  • Anti-inflammatory
  • Supports cartilage matrix

Evidence Quality

Evidence Grade B

European OA treatment

Safety & Contraindications

Serious Warnings
  • None
Contraindications
  • Soy allergy
Common Side Effects
  • GI upset
Pregnancy & Breastfeeding

Insufficient data

Liver & Kidney Notes

Safe

Interactions

💊 Medications
  • None significant
🧪 Supplements
  • Works with glucosamine
🍽️ Food & Alcohol
  • Take with food

Stacking & Synergies

Avoid Combining With
None
Best Goal Synergies
OACartilage

Buying Guide

What to Look For
  • Standardized extract
Standardization Markers
ASU content1:2 ratio avocado:soy
Adulteration risk
Low
Practical Notes
  • Used as prescription in France
  • 300mg daily standard
Tags
jointcartilageOAlipid

More in Joint Health

Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Avocado-Soy Unsaponifiables (ASU) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/avocado-soy-unsaponifiables

Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.