Broccoli
Antioxidant
Also known as: Sulforaphane, Brassica oleracea, Broccoli Powder, Broccoli extract, Cruciferous vegetable powder
A
Grade A💊 50-100 mg sulforaphane equivalent🎯 8 primary uses🔗 3 synergies✅ Generally safe
Levels upHeart & Longevity+50 pts
Overview
Broccoli powder is a whole-food derived ingredient rich in sulforaphane, glucosinolates, and polyphenols that support antioxidant and detoxification pathways. Evidence supports potential benefits for cellular health and inflammatory response, though most human research uses fresh broccoli or concentrated extracts rather than powder forms.
Primary Uses
Detoxification supportAntioxidantCellular healthLiver supportAntioxidant supportDetoxification (phase 2 enzyme support)Anti-inflammatory supportGeneral nutritional supplementation
Frequently Asked About Broccoli
How much Broccoli should I take?
The typical effective range is 50-100 mg sulforaphane equivalent. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Broccoli?
With meals. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Broccoli with food?
Yes.
Does Broccoli interact with medications?
Yes — known interactions include May affect drug metabolism via detox enzymes. If you take any prescription medication, talk to your doctor or pharmacist before starting Broccoli.
What does Broccoli pair well with?
Broccoli stacks well with NAC, Glutathione, and Milk Thistle — these combinations either improve absorption or work synergistically toward common goals.
What are the side effects of Broccoli?
Most people tolerate Broccoli well. The most commonly reported side effects are GI upset and Gas. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
50-100 mg sulforaphane equivalent
Timing
With meals
With food
Yes
Duration
Safe for long-term use
Special Populations
Detox support seekers
Research & Studies
Search the literature now
We haven’t curated landmark studies for Broccoliyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Mechanism of Action
- • Activates Nrf2 pathway
- • Upregulates detox enzymes
- • Supports glutathione production
Evidence Quality
Evidence Grade A
Strong evidence for Nrf2 activation and detoxification support
Safety & Contraindications
Common Side Effects
- • GI upset
- • Gas
Pregnancy & Breastfeeding
Consult healthcare provider
Liver & Kidney Notes
Supports liver function
Interactions
💊 Medications
- • May affect drug metabolism via detox enzymes
🧪 Supplements
- • Synergistic with NAC, glutathione
Stacking & Synergies
Pairs Well With
Best Goal Synergies
DetoxificationLiver health
Buying Guide
What to Look For
- • Myrosinase included or stabilized sulforaphane
Standardization Markers
Sulforaphane or glucoraphanin content
Adulteration risk
Low
Practical Notes
- • Myrosinase enzyme needed to convert glucoraphanin
- • Sprouts have 20-100x more than mature broccoli
Tags
detoxantioxidantNrf2cruciferouswhole-foodplant-baseddetoxificationsulforaphane source
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Last reviewed: September 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, September). Broccoli — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/broccoli
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.