Copper (Bisglycinate)
Mineral
Also known as: Copper glycinate, Chelated copper
A
Grade A💊 1-2 mg daily🎯 4 primary uses🔗 2 synergies⚠️ Review warnings
Levels upNutrition+50 pts
Overview
Essential trace mineral needed to balance zinc supplementation. Supports energy, connective tissue, and iron metabolism.
Primary Uses
Zinc balanceEnergy productionConnective tissueIron metabolism
Frequently Asked About Copper (Bisglycinate)
How much Copper (Bisglycinate) should I take?
The typical effective range is 1-2 mg daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Copper (Bisglycinate)?
Separate from zinc. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Copper (Bisglycinate) with food?
Optional.
Does Copper (Bisglycinate) interact with medications?
Yes — known interactions include Penicillamine depletes. If you take any prescription medication, talk to your doctor or pharmacist before starting Copper (Bisglycinate).
What does Copper (Bisglycinate) pair well with?
Copper (Bisglycinate) stacks well with Zinc (separate times) and Vitamin C — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Copper (Bisglycinate)?
Copper (Bisglycinate) should be avoided or used with caution by people with Wilson's disease. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Copper (Bisglycinate)?
Most people tolerate Copper (Bisglycinate) well. The most commonly reported side effects are Nausea at high doses. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
1-2 mg daily
Timing
Separate from zinc
With food
Optional
Duration
Needed with zinc supplementation
Special Populations
Those supplementing >15mg zinc
Research & Studies
Search the literature now
We haven’t curated landmark studies for Copper (Bisglycinate)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Search Copper (Bisglycinate) research
Mechanism of Action
- • Cofactor for cytochrome c oxidase
- • Essential for collagen cross-linking
- • Required for iron absorption
Evidence Quality
Evidence Grade A
Essential when supplementing zinc
Safety & Contraindications
Serious Warnings
- • Wilson's disease contraindicated
- • Don't exceed 10mg
Contraindications
- • Wilson's disease
Common Side Effects
- • Nausea at high doses
Pregnancy & Breastfeeding
Consult healthcare provider
Liver & Kidney Notes
Avoid in Wilson's disease
Interactions
💊 Medications
- • Penicillamine depletes
🧪 Supplements
- • Balance with zinc 15:1
- • Competes with zinc
🍽️ Food & Alcohol
- • No interactions
Stacking & Synergies
Pairs Well With
Avoid Combining With
Zinc at same time
Best Goal Synergies
Zinc balanceEnergy
Buying Guide
What to Look For
- • Chelated form
Standardization Markers
mg copper
Adulteration risk
Low
Practical Notes
- • Essential with zinc >15mg long-term
- • Typical ratio 15:1 zinc:copper
Tags
mineraltrace mineralzinc balance
More in Mineral
Other ingredients in the Mineral category.
Boron
Trace mineral supporting bone health, cognitive function, and hormone metabolism. May support testosterone in deficient states.
Calcium
Essential mineral for bone health, muscle function, nerve signaling, and blood clotting.
Calcium Carbonate
Common, economical calcium form with highest elemental calcium percentage. Requires stomach acid for absorption.
Calcium Citrate
Well-absorbed calcium form that doesn't require stomach acid. Better for those on acid-reducing medications.
Chloride
Essential electrolyte mineral that works with sodium and potassium to maintain fluid balance, nerve transmission, and stomach acid production.
Chromium Picolinate
Trace mineral for insulin sensitivity and blood sugar regulation. Popular for carb cravings.
Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Copper (Bisglycinate) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/copper-bisglycinate
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.