Copper (Bisglycinate)

Mineral

Also known as: Copper glycinate, Chelated copper

Grade A

💊 1-2 mg daily🎯 4 primary uses🔗 2 synergies⚠️ Review warnings

Overview

Essential trace mineral needed to balance zinc supplementation. Supports energy, connective tissue, and iron metabolism.

Primary Uses

Zinc balanceEnergy productionConnective tissueIron metabolism

Frequently Asked About Copper (Bisglycinate)

How much Copper (Bisglycinate) should I take?

The typical effective range is 1-2 mg daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.

When is the best time to take Copper (Bisglycinate)?

Separate from zinc. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.

Should I take Copper (Bisglycinate) with food?

Optional.

Does Copper (Bisglycinate) interact with medications?

Yes — known interactions include Penicillamine depletes. If you take any prescription medication, talk to your doctor or pharmacist before starting Copper (Bisglycinate).

What does Copper (Bisglycinate) pair well with?

Copper (Bisglycinate) stacks well with Zinc (separate times) and Vitamin C — these combinations either improve absorption or work synergistically toward common goals.

Who should not take Copper (Bisglycinate)?

Copper (Bisglycinate) should be avoided or used with caution by people with Wilson's disease. Pregnant or breastfeeding women should consult a healthcare provider before use.

What are the side effects of Copper (Bisglycinate)?

Most people tolerate Copper (Bisglycinate) well. The most commonly reported side effects are Nausea at high doses. Side effects are usually dose-dependent — lowering the dose often resolves them.

Dosage

Typical range

1-2 mg daily

Timing

Separate from zinc

With food

Optional

Duration

Needed with zinc supplementation

Special Populations

Those supplementing >15mg zinc

Research & Studies

Search the literature now

We haven’t curated landmark studies for Copper (Bisglycinate)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.

Search Copper (Bisglycinate) research

PubMed (RCTs) ↗Randomized trials PubMed (all) ↗Full literature Cochrane Reviews ↗Systematic reviews Examine.com ↗Research summaries

Browse all curated studies →

Mechanism of Action

• Cofactor for cytochrome c oxidase
• Essential for collagen cross-linking
• Required for iron absorption

Evidence Quality

Evidence Grade A

Essential when supplementing zinc

Safety & Contraindications

Serious Warnings

• Wilson's disease contraindicated
• Don't exceed 10mg

Contraindications

• Wilson's disease

Common Side Effects

• Nausea at high doses

Pregnancy & Breastfeeding

Consult healthcare provider

Liver & Kidney Notes

Avoid in Wilson's disease

Interactions

💊 Medications

• Penicillamine depletes

🧪 Supplements

• Balance with zinc 15:1
• Competes with zinc

🍽️ Food & Alcohol

• No interactions

Stacking & Synergies

Pairs Well With

Zinc (separate times) ↗Vitamin C ↗

Avoid Combining With

Zinc at same time

Best Goal Synergies

Zinc balanceEnergy

Buying Guide

What to Look For

• Chelated form

Standardization Markers

mg copper

Adulteration risk

Low

Practical Notes

• Essential with zinc >15mg long-term
• Typical ratio 15:1 zinc:copper

More in Mineral

Other ingredients in the Mineral category.

Boron

Trace mineral supporting bone health, cognitive function, and hormone metabolism. May support testosterone in deficient states.

Calcium

Essential mineral for bone health, muscle function, nerve signaling, and blood clotting.

Calcium Carbonate

Common, economical calcium form with highest elemental calcium percentage. Requires stomach acid for absorption.

Calcium Citrate

Well-absorbed calcium form that doesn't require stomach acid. Better for those on acid-reducing medications.

Chloride

Essential electrolyte mineral that works with sodium and potassium to maintain fluid balance, nerve transmission, and stomach acid production.

Chromium Picolinate

Trace mineral for insulin sensitivity and blood sugar regulation. Popular for carb cravings.

Browse all Mineral ingredients →

Last reviewed: August 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.

Cite this page

Formulate Research Team. (2026, August). Copper (Bisglycinate) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/copper-bisglycinate

Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.

Formulate Research Team. (2026, August). Copper (Bisglycinate) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/copper-bisglycinate