DGL (Deglycyrrhizinated Licorice)
Digestive Aid
Also known as: Deglycyrrhizinated licorice, DGL licorice, Gut-safe licorice
B
Grade B💊 380-760mg chewed 20 minutes before meals, up to 3x daily🎯 4 primary uses🔗 3 synergies⚠️ Review warnings
Levels upNutrition+50 pts
Overview
Licorice with glycyrrhizin removed, safe for long-term use to soothe and protect stomach lining.
Primary Uses
Stomach liningUlcer supportHeartburnGut soothing
Frequently Asked About DGL (Deglycyrrhizinated Licorice)
How much DGL (Deglycyrrhizinated Licorice) should I take?
The typical effective range is 380-760mg chewed 20 minutes before meals, up to 3x daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take DGL (Deglycyrrhizinated Licorice)?
Before meals and bedtime. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take DGL (Deglycyrrhizinated Licorice) with food?
Before meals.
Does DGL (Deglycyrrhizinated Licorice) interact with medications?
Yes — known interactions include Generally safe and May help reduce NSAID damage. If you take any prescription medication, talk to your doctor or pharmacist before starting DGL (Deglycyrrhizinated Licorice).
What does DGL (Deglycyrrhizinated Licorice) pair well with?
DGL (Deglycyrrhizinated Licorice) stacks well with Zinc carnosine, Mastic gum, and Slippery elm — these combinations either improve absorption or work synergistically toward common goals.
Who should not take DGL (Deglycyrrhizinated Licorice)?
DGL (Deglycyrrhizinated Licorice) should be avoided or used with caution by people with None for DGL specifically. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of DGL (Deglycyrrhizinated Licorice)?
Most people tolerate DGL (Deglycyrrhizinated Licorice) well. The most commonly reported side effects are Rare at DGL form. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
380-760mg chewed 20 minutes before meals, up to 3x daily
Timing
Before meals and bedtime
With food
Before meals
Duration
Long-term use safe (glycyrrhizin removed)
Special Populations
Ulcers, GERD, gastritis, H. pylori adjunct
Research & Studies
Search the literature now
We haven’t curated landmark studies for DGL (Deglycyrrhizinated Licorice)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Search DGL (Deglycyrrhizinated Licorice) research
Mechanism of Action
- • Stimulates mucus production
- • Protects stomach lining
- • Soothes GI tract
- • Glycyrrhizin removed for safety
Evidence Quality
Evidence Grade B
Good evidence for GI mucosal support
Safety & Contraindications
Serious Warnings
- • Ensure it's DGL, not whole licorice
Contraindications
- • None for DGL specifically
Common Side Effects
- • Rare at DGL form
Pregnancy & Breastfeeding
Consult healthcare provider
Liver & Kidney Notes
Safe (glycyrrhizin removed)
Interactions
💊 Medications
- • Generally safe
- • May help reduce NSAID damage
🧪 Supplements
- • Synergistic with zinc carnosine, mastic gum
🍽️ Food & Alcohol
- • Before meals
Stacking & Synergies
Pairs Well With
Avoid Combining With
None
Best Goal Synergies
Stomach liningUlcer supportGERD
Buying Guide
What to Look For
- • Verified DGL
- • Chewable form preferred
Standardization Markers
DGL contentGlycyrrhizin removed
Adulteration risk
Low
Practical Notes
- • Chew tablets for best effect
- • Safe long-term (not whole licorice)
- • Before meals
Tags
digestivemucosalulcerheartburn
Top Products with DGL (Deglycyrrhizinated Licorice)
Highest-scored catalog products containing DGL (Deglycyrrhizinated Licorice), ranked by our scoring engine.
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More in Digestive Aid
Other ingredients in the Digestive Aid category.
Apple Cider Vinegar
Apple cider vinegar powder is a dehydrated form of fermented apple juice containing acetic acid and other compounds. Popular in wellness contexts for potential digestive and metabolic support, though human clinical evidence remains limited.
Mastic Gum
Mediterranean tree resin with antimicrobial properties, traditionally used for stomach ulcers and H. pylori.
Last reviewed: September 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, September). DGL (Deglycyrrhizinated Licorice) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/dgl-licorice
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.