Also known as: EPO, GLA, Oenothera biennis oil
GLA-rich oil traditionally used for PMS breast tenderness and hormonal symptoms.
2-3 cycles for effect
PMS, especially breast tenderness
We haven’t curated landmark studies for Evening Primrose Oil (PMS)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Mixed evidence, traditionally used for PMS breast symptoms
Avoid in pregnancy
Safe
In-depth guides covering Evening Primrose Oil (PMS) — protocols, comparisons, and use cases.
Formulate Research Team. (2026, September). Evening Primrose Oil (PMS) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/evening-primrose-pms
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.