Iron (Bisglycinate)
Mineral
Also known as: Ferrochel, Iron glycinate, Chelated iron
A
Grade A💊 18-65 mg daily based on need🎯 4 primary uses🔗 3 synergies⚠️ Review warnings
Levels upNutrition+50 pts
Overview
Highly absorbable iron form that's gentle on the stomach. Best choice for those who experience GI upset with other iron forms.
Primary Uses
AnemiaIron deficiencyEnergyWomen's health
Frequently Asked About Iron (Bisglycinate)
How much Iron (Bisglycinate) should I take?
The typical effective range is 18-65 mg daily based on need. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Iron (Bisglycinate)?
Empty stomach or with vitamin C. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Iron (Bisglycinate) with food?
Can take with food if GI upset.
Does Iron (Bisglycinate) interact with medications?
Yes — known interactions include Reduces levothyroxine absorption and Reduces antibiotic absorption. If you take any prescription medication, talk to your doctor or pharmacist before starting Iron (Bisglycinate).
What does Iron (Bisglycinate) pair well with?
Iron (Bisglycinate) stacks well with Vitamin C, B12, and Folate — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Iron (Bisglycinate)?
Iron (Bisglycinate) should be avoided or used with caution by people with Hemochromatosis and Non-deficient states. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Iron (Bisglycinate)?
Most people tolerate Iron (Bisglycinate) well. The most commonly reported side effects are Less constipation than other forms. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
18-65 mg daily based on need
Timing
Empty stomach or with vitamin C
With food
Can take with food if GI upset
Duration
Until stores replete
Special Populations
Menstruating women, vegetarians
Research & Studies
Search the literature now
We haven’t curated landmark studies for Iron (Bisglycinate)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Search Iron (Bisglycinate) research
Mechanism of Action
- • Glycinate chelation enhances absorption
- • Doesn't cause constipation like other forms
- • Absorbed intact through intestinal cells
Evidence Quality
Evidence Grade A
Well-absorbed with minimal GI effects
Safety & Contraindications
Serious Warnings
- • Iron overload if not deficient
- • Hemochromatosis
Contraindications
- • Hemochromatosis
- • Non-deficient states
Common Side Effects
- • Less constipation than other forms
Pregnancy & Breastfeeding
Often needed, confirm deficiency
Liver & Kidney Notes
Avoid iron overload
Interactions
💊 Medications
- • Reduces levothyroxine absorption
- • Reduces antibiotic absorption
🧪 Supplements
- • Vitamin C enhances absorption
- • Separate from calcium, zinc
🍽️ Food & Alcohol
- • Tannins reduce absorption
Stacking & Synergies
Pairs Well With
Best Goal Synergies
Iron deficiencyEnergy
Buying Guide
What to Look For
- • Ferrochel or bisglycinate form
Standardization Markers
Elemental iron mg
Adulteration risk
Low
Practical Notes
- • Confirm deficiency before supplementing
- • Gentle form for sensitive stomachs
Tags
mineralenergywomen's health
Related Guides
In-depth guides covering Iron (Bisglycinate) — protocols, comparisons, and use cases.
More in Mineral
Other ingredients in the Mineral category.
Boron
Trace mineral supporting bone health, cognitive function, and hormone metabolism. May support testosterone in deficient states.
Calcium
Essential mineral for bone health, muscle function, nerve signaling, and blood clotting.
Calcium Carbonate
Common, economical calcium form with highest elemental calcium percentage. Requires stomach acid for absorption.
Calcium Citrate
Well-absorbed calcium form that doesn't require stomach acid. Better for those on acid-reducing medications.
Chloride
Essential electrolyte mineral that works with sodium and potassium to maintain fluid balance, nerve transmission, and stomach acid production.
Chromium Picolinate
Trace mineral for insulin sensitivity and blood sugar regulation. Popular for carb cravings.
Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Iron (Bisglycinate) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/iron-bisglycinate
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.