Also known as: Arginine, L-Arginine HCl, L-Arginine Hydrochloride, Arginine HCl
A conditionally essential amino acid that serves as a precursor to nitric oxide, supporting vasodilation and blood flow. Most evidence supports benefits for endothelial function and exercise performance, though clinical results are mixed.
Safe long-term
Cardiovascular, athletes, ED
We haven’t curated landmark studies for L-Arginineyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Nitric oxide precursor
Consult healthcare provider
Caution kidney disease
Other ingredients in the Amino Acid category.
Formulate Research Team. (2026, September). L-Arginine — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/l-arginine
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.