Also known as: Crocus sativus, Kesar, Saffron, Za'faran, Saffron Extract (Crocus sativus)
A standardized saffron stigma extract containing 7.5% crocins and 1.0% safranals, the primary active compounds associated with mood, vision, and antioxidant support. One of the most expensive spices with a growing clinical research base.
4-6 weeks for mood effects
Mild depression, PMS
We haven’t curated landmark studies for Saffron Extractyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Well-studied for depression
Avoid therapeutic doses
Safe
Other ingredients in the Nootropic category.
Formulate Research Team. (2026, September). Saffron Extract — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/saffron
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.