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Magnesium Glycinate

Mineral

Also known as: Chelated magnesium

A
Grade A
๐Ÿ’Š 200-400 mg elemental Mg daily๐ŸŽฏ 4 primary uses๐Ÿ”— 3 synergiesโš ๏ธ Review warnings

Overview

Highly bioavailable magnesium chelated with glycine. Excellent for sleep, relaxation, and those with sensitive stomachs.

Primary Uses
Sleep supportMuscle relaxationStress/anxietyMagnesium repletion

Dosage

Typical range
200-400 mg elemental Mg daily
Timing
Evening, 1-2h before bed
With food
Optional
Duration

Safe long-term

Special Populations

Sensitive stomachs

Mechanism of Action

  • โ€ข Glycine chelation enhances absorption
  • โ€ข Magnesium regulates GABA
  • โ€ข Glycine independently calming

Evidence Quality

Evidence Grade A

Excellent bioavailability and tolerability

Safety & Contraindications

Serious Warnings
  • โ€ข Caution in kidney disease
Contraindications
  • โ€ข Severe kidney failure
Common Side Effects
  • โ€ข Very well tolerated
Pregnancy & Breastfeeding

Safe, important

Liver & Kidney Notes

Avoid severe kidney disease

Interactions

๐Ÿ’Š Medications
  • โ€ข Separate from antibiotics 2h
๐Ÿงช Supplements
  • โ€ข Works with B6
  • โ€ข Separate from zinc
๐Ÿฝ๏ธ Food & Alcohol
  • โ€ข No interactions

Stacking & Synergies

Pairs Well With
Vitamin D3B6L-theanine
Avoid Combining With
Calcium same time
Best Goal Synergies
SleepStressMuscle recovery

Buying Guide

What to Look For
  • โ€ข Elemental Mg amount
Standardization Markers
Elemental Mg stated
Adulteration risk
Low
Practical Notes
  • โ€ข Best form for sleep/relaxation
  • โ€ข Look at elemental Mg, not compound weight
Tags
mineralsleeprelaxationhighly bioavailable

Frequently Asked About Magnesium Glycinate

How much Magnesium Glycinate should I take?
The typical effective range is 200-400 mg elemental Mg daily. Individual needs vary based on age, body weight, diet, and goals โ€” start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Magnesium Glycinate?
Evening, 1-2h before bed. Consistency matters more than perfect timing โ€” pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Magnesium Glycinate with food?
Optional.
Does Magnesium Glycinate interact with medications?
Yes โ€” known interactions include Separate from antibiotics 2h. If you take any prescription medication, talk to your doctor or pharmacist before starting Magnesium Glycinate.
What does Magnesium Glycinate pair well with?
Magnesium Glycinate stacks well with Vitamin D3, B6, and L-theanine โ€” these combinations either improve absorption or work synergistically toward common goals.
Who should not take Magnesium Glycinate?
Magnesium Glycinate should be avoided or used with caution by people with Severe kidney failure. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Magnesium Glycinate?
Most people tolerate Magnesium Glycinate well. The most commonly reported side effects are Very well tolerated. Side effects are usually dose-dependent โ€” lowering the dose often resolves them.

Related Guides

In-depth guides covering Magnesium Glycinate โ€” protocols, comparisons, and use cases.

Educational content based on published research and our scoring methodology. Not medical advice โ€” consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.