Quercetin

Antioxidant

Also known as: Quercetin dihydrate, Quercetin phytosome, Quercetin Phytosome® (Quercefit®), Quercefit, Sophora japonica extract

Grade B

💊 500-1000 mg daily🎯 9 primary uses🔗 3 synergies⚠️ Review warnings

Overview

Quercetin is a flavonoid antioxidant with anti-inflammatory properties; the Phytosome® delivery system uses phospholipids to enhance absorption compared to standard quercetin. Evidence supports potential benefits for allergies, cardiovascular health, and exercise recovery, though human clinical data remains moderate.

Primary Uses

AllergiesInflammationImmune supportSenolyticAntioxidant supportAnti-inflammatory responseAllergy symptom managementCardiovascular healthExercise recovery

Dosage

Typical range

500-1000 mg daily

Timing

Divided doses

With food

Yes

Dose Tiers

Moderate

500 mg/day

Optimal

500 mg twice daily with bromelain

Therapeutic

1,000 mg twice daily

Upper Limit

No established UL

Duration

Safe long-term

Special Populations

Allergies, inflammation

Mechanism of Action

• Mast cell stabilizer
• Inhibits inflammatory enzymes
• Senolytic (clears senescent cells)
• Zinc ionophore

Evidence Quality

Evidence Grade B

Broad anti-inflammatory effects

Safety & Contraindications

Serious Warnings

• None

Contraindications

• None

Common Side Effects

• Well tolerated

Pregnancy & Breastfeeding

Consult healthcare provider

Liver & Kidney Notes

Safe

Interactions

💊 Medications

• Antibiotics - enhances some
• Cyclosporine

🧪 Supplements

• Works with vitamin C, bromelain

🍽️ Food & Alcohol

• Onions, apples are sources

Stacking & Synergies

Pairs Well With

BromelainVitamin CZinc

Avoid Combining With

None

Best Goal Synergies

AllergiesInflammation

Buying Guide

What to Look For

• Phytosome or with bromelain

Standardization Markers

Quercetin contentForm

Adulteration risk

Low

Practical Notes

• Low bioavailability - phytosome helps
• Natural antihistamine

Frequently Asked About Quercetin

How much Quercetin should I take?

The typical effective range is 500 mg twice daily with bromelain. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.

When is the best time to take Quercetin?

Divided doses. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.

Should I take Quercetin with food?

Yes.

Does Quercetin interact with medications?

Yes — known interactions include Antibiotics - enhances some and Cyclosporine. If you take any prescription medication, talk to your doctor or pharmacist before starting Quercetin.

What does Quercetin pair well with?

Quercetin stacks well with Bromelain, Vitamin C, and Zinc — these combinations either improve absorption or work synergistically toward common goals.

Who should not take Quercetin?

Quercetin should be avoided or used with caution by people with None. Pregnant or breastfeeding women should consult a healthcare provider before use.

What are the side effects of Quercetin?

Most people tolerate Quercetin well. The most commonly reported side effects are Well tolerated. Side effects are usually dose-dependent — lowering the dose often resolves them.

Top Products with Quercetin

Highest-scored catalog products containing Quercetin, ranked by our scoring engine.

Browse all Quercetin products →

Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.