Sulforaphane Glucosinolate (SGS)
Phytonutrient
Also known as: SGS, Glucosinolate, Sulforaphane glucosinolate, Broccoli seed extract
A
Grade A💊 30-100mg glucosinolate daily🎯 4 primary uses🔗 3 synergies⚠️ Review warnings
Levels upNutrition+50 pts
Overview
Stable sulforaphane precursor from broccoli seeds. Powerful Nrf2 activator for detoxification and cellular protection.
Primary Uses
Nrf2 activationDetoxificationCellular protectionPhase 2 enzyme induction
Frequently Asked About Sulforaphane Glucosinolate (SGS)
How much Sulforaphane Glucosinolate (SGS) should I take?
The typical effective range is 30-100mg glucosinolate daily. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Sulforaphane Glucosinolate (SGS)?
With meals. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Sulforaphane Glucosinolate (SGS) with food?
Yes.
Does Sulforaphane Glucosinolate (SGS) interact with medications?
Yes — known interactions include May affect drug metabolism. If you take any prescription medication, talk to your doctor or pharmacist before starting Sulforaphane Glucosinolate (SGS).
What does Sulforaphane Glucosinolate (SGS) pair well with?
Sulforaphane Glucosinolate (SGS) stacks well with NAC, Milk thistle, and DIM — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Sulforaphane Glucosinolate (SGS)?
Sulforaphane Glucosinolate (SGS) should be avoided or used with caution by people with Thyroid issues (high doses). Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Sulforaphane Glucosinolate (SGS)?
Most people tolerate Sulforaphane Glucosinolate (SGS) well. The most commonly reported side effects are GI upset. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
30-100mg glucosinolate daily
Timing
With meals
With food
Yes
Duration
Safe long-term
Special Populations
Detox support
Research & Studies
Search the literature now
We haven’t curated landmark studies for Sulforaphane Glucosinolate (SGS)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Search Sulforaphane Glucosinolate (SGS) research
Mechanism of Action
- • Converts to sulforaphane
- • Activates Nrf2 pathway
- • Induces phase 2 detox enzymes
- • Supports glutathione
Evidence Quality
Evidence Grade A
Strong evidence for Nrf2 activation and detox support
Safety & Contraindications
Serious Warnings
- • May affect thyroid at very high doses
Contraindications
- • Thyroid issues (high doses)
Common Side Effects
- • GI upset
Pregnancy & Breastfeeding
Consult healthcare provider
Liver & Kidney Notes
Supports liver
Interactions
💊 Medications
- • May affect drug metabolism
🧪 Supplements
- • Works with NAC, glutathione support
🍽️ Food & Alcohol
- • With food
Stacking & Synergies
Pairs Well With
Avoid Combining With
None
Best Goal Synergies
DetoxificationNrf2 activation
Buying Guide
What to Look For
- • Standardized SGS content
Standardization Markers
SGS contentGlucosinolate %
Adulteration risk
Low
Practical Notes
- • Stable form of sulforaphane precursor
- • Used in MediClear formulas
Tags
nrf2detoxcruciferousantioxidant
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Browse all Phytonutrient ingredients →Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Sulforaphane Glucosinolate (SGS) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/sgs-sulforaphane-glucosinolate
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.