Tribulus Terrestris
Hormone Support
Also known as: Puncture vine, Gokshura
C
Grade C💊 250-750mg extract🎯 3 primary uses🔗 2 synergies⚠️ Review warnings
Levels upStress & Resilience+50 pts
Overview
Traditional herb for libido. Less evidence for testosterone but may help libido.
Primary Uses
LibidoSexual functionTestosterone (weak)
Frequently Asked About Tribulus Terrestris
How much Tribulus Terrestris should I take?
The typical effective range is 250-750mg extract. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Tribulus Terrestris?
With meals. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Tribulus Terrestris with food?
Yes.
Does Tribulus Terrestris interact with medications?
Yes — known interactions include Diabetes meds and Blood pressure meds. If you take any prescription medication, talk to your doctor or pharmacist before starting Tribulus Terrestris.
What does Tribulus Terrestris pair well with?
Tribulus Terrestris stacks well with Maca and Ashwagandha — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Tribulus Terrestris?
Tribulus Terrestris should be avoided or used with caution by people with Hormone-sensitive conditions. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Tribulus Terrestris?
Most people tolerate Tribulus Terrestris well. The most commonly reported side effects are GI upset and Sleep disturbances. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
250-750mg extract
Timing
With meals
With food
Yes
Duration
Several weeks
Special Populations
Libido support
Research & Studies
Search the literature now
We haven’t curated landmark studies for Tribulus Terrestrisyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Search Tribulus Terrestris research
Mechanism of Action
- • Contains steroidal saponins
- • May affect androgen receptors
- • Libido effects separate from testosterone
Evidence Quality
Evidence Grade C
Better evidence for libido than testosterone
Safety & Contraindications
Serious Warnings
- • None significant
Contraindications
- • Hormone-sensitive conditions
Common Side Effects
- • GI upset
- • Sleep disturbances
Pregnancy & Breastfeeding
Avoid
Liver & Kidney Notes
Some kidney concerns in animals
Interactions
💊 Medications
- • Diabetes meds
- • Blood pressure meds
🧪 Supplements
- • Other testosterone herbs
🍽️ Food & Alcohol
- • No interactions
Stacking & Synergies
Buying Guide
What to Look For
- • Standardized saponins
Standardization Markers
Saponin content
Adulteration risk
Moderate
Practical Notes
- • Better for libido than testosterone
- • Traditional use extensive
Tags
libidotestosteronesexual functiontraditional
More in Hormone Support
Other ingredients in the Hormone Support category.
Black Cohosh
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DHEA (Dehydroepiandrosterone)
DHEA is an endogenous adrenal hormone and precursor to testosterone and estrogen, with declining levels in aging. Supplementation aims to restore youthful hormone levels and support energy, mood, and sexual function.
Dong Quai
Dong quai (Angelica sinensis) is a traditional Chinese medicinal root used to support women's health and hormonal balance, particularly during menopause and menstrual cycles. Scientific evidence for efficacy is mixed, with limited high-quality clinical trials.
Fadogia Agrestis
Nigerian shrub gaining popularity for testosterone. Limited human research, animal studies promising.
Fadogia Agrestis
African herb gaining popularity for testosterone support, though human evidence is limited.
Fenugreek
Seed extract that may support testosterone and libido. Also supports blood sugar.
Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Tribulus Terrestris — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/tribulus
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.