Tribulus Terrestris

Hormone Support

Also known as: Puncture vine, Gokshura

Grade C

💊 250-750mg extract🎯 3 primary uses🔗 2 synergies⚠️ Review warnings

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Levels upStress & Mood+50 pts

Overview

Traditional herb for libido. Less evidence for testosterone but may help libido.

Primary Uses

LibidoSexual functionTestosterone (weak)

Frequently Asked About Tribulus Terrestris

How much Tribulus Terrestris should I take?

The typical effective range is 250-750mg extract. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.

When is the best time to take Tribulus Terrestris?

With meals. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.

Should I take Tribulus Terrestris with food?

Yes.

Does Tribulus Terrestris interact with medications?

Yes — known interactions include Diabetes meds and Blood pressure meds. If you take any prescription medication, talk to your doctor or pharmacist before starting Tribulus Terrestris.

What does Tribulus Terrestris pair well with?

Tribulus Terrestris stacks well with Maca and Ashwagandha — these combinations either improve absorption or work synergistically toward common goals.

Who should not take Tribulus Terrestris?

Tribulus Terrestris should be avoided or used with caution by people with Hormone-sensitive conditions. Pregnant or breastfeeding women should consult a healthcare provider before use.

What are the side effects of Tribulus Terrestris?

Most people tolerate Tribulus Terrestris well. The most commonly reported side effects are GI upset and Sleep disturbances. Side effects are usually dose-dependent — lowering the dose often resolves them.

Dosage

Typical range

250-750mg extract

Timing

With meals

With food

Yes

Duration

Several weeks

Special Populations

Libido support

Research & Studies

Search the literature now

We haven’t curated landmark studies for Tribulus Terrestrisyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.

Search Tribulus Terrestris research

PubMed (RCTs) ↗Randomized trials PubMed (all) ↗Full literature Cochrane Reviews ↗Systematic reviews Examine.com ↗Research summaries

Browse all curated studies →

Mechanism of Action

• Contains steroidal saponins
• May affect androgen receptors
• Libido effects separate from testosterone

Evidence Quality

Evidence Grade C

Better evidence for libido than testosterone

Safety & Contraindications

Serious Warnings

• None significant

Contraindications

• Hormone-sensitive conditions

Common Side Effects

• GI upset
• Sleep disturbances

Pregnancy & Breastfeeding

Avoid

Liver & Kidney Notes

Some kidney concerns in animals

Interactions

💊 Medications

• Diabetes meds
• Blood pressure meds

🧪 Supplements

• Other testosterone herbs

🍽️ Food & Alcohol

• No interactions

Stacking & Synergies

Pairs Well With

Maca ↗Ashwagandha ↗

Avoid Combining With

Nothing specific

Best Goal Synergies

Libido

Buying Guide

What to Look For

• Standardized saponins

Standardization Markers

Saponin content

Adulteration risk

Moderate

Practical Notes

• Better for libido than testosterone
• Traditional use extensive

More in Hormone Support

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DHEA is an endogenous adrenal hormone and precursor to testosterone and estrogen, with declining levels in aging. Supplementation aims to restore youthful hormone levels and support energy, mood, and sexual function.

Dong Quai

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Fadogia Agrestis

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Fadogia Agrestis

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Fenugreek

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Last reviewed: September 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.

Cite this page

Formulate Research Team. (2026, September). Tribulus Terrestris — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/tribulus

Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.