Skip to main content
Skip to content
Biochemical Pathway

Clotting

Vitamin K-dependent factors II/VII/IX/X, fibrin formation

Blood clotting is a tightly controlled cascade — you need it to fire fast at a wound but never inappropriately inside a vessel. Vitamin K is the load-bearing nutrient: it activates clotting factors II, VII, IX, and X (the 'K' literally stands for Koagulation), which is exactly why the drug warfarin works by blocking it. Calcium is a required cofactor at several steps of the cascade, and omega-3s gently modulate platelet aggregation. The same vitamin K that drives clotting also activates the proteins that keep calcium in bone and out of arteries — so it sits at the intersection of clotting, bone, and vascular health.

See your coverage for the Clotting pathway

How your supplements + diet feed this pathway right now — the cofactors driving it, where the gaps are, and your own lab readouts.

View →
Primary cofactors

The load-bearing nutrients — if these are deficient, this pathway slows down. Click any to see daily targets, food sources, and supplements that supply it.

Additional cofactors

Nutrients that contribute to this pathway but aren’t the single load-bearing inputs.

Biomarkers on this pathway

Lab markers that report on how well this pathway is running. When one of these is out of range, this pathway is often where the upstream issue lives.

🩸 Platelets

Save a lab session under My Journey → Biomarkers to see your own values for these.

Body systems that depend on this pathway
Related pathways

Pathways that share a load-bearing cofactor with this one.