Passionflower
Sleep
Also known as: Maypop, Passiflora incarnata, Passionflower 10:1 Extract (Passiflora incarnata), Passion Flower, Purple Passionflower
B
Grade B💊 250-500 mg extract or as tea🎯 6 primary uses🔗 3 synergies⚠️ Review warnings
Levels upSleep+50 pts
Overview
Passionflower is a traditional herbal anxiolytic used to support relaxation and sleep quality. A 10:1 extract concentrate provides a potent dose; moderate clinical evidence supports mild anxiolytic and sedative effects.
Primary Uses
AnxietySleepRelaxationAnxiety and nervous tensionSleep supportRestlessness and irritability
Frequently Asked About Passionflower
How much Passionflower should I take?
The typical effective range is 250-500 mg extract or as tea. Individual needs vary based on age, body weight, diet, and goals — start at the lower end and adjust based on response. Always consult a healthcare provider before starting a new supplement.
When is the best time to take Passionflower?
Evening or as needed. Consistency matters more than perfect timing — pick a daily anchor (e.g. with breakfast or before bed) and stick with it.
Should I take Passionflower with food?
Optional.
Does Passionflower interact with medications?
Yes — known interactions include CNS depressants additive and Blood thinners. If you take any prescription medication, talk to your doctor or pharmacist before starting Passionflower.
What does Passionflower pair well with?
Passionflower stacks well with Valerian, Lemon balm, and L-theanine — these combinations either improve absorption or work synergistically toward common goals.
Who should not take Passionflower?
Passionflower should be avoided or used with caution by people with None. Pregnant or breastfeeding women should consult a healthcare provider before use.
What are the side effects of Passionflower?
Most people tolerate Passionflower well. The most commonly reported side effects are Drowsiness and Dizziness. Side effects are usually dose-dependent — lowering the dose often resolves them.
Dosage
Typical range
250-500 mg extract or as tea
Timing
Evening or as needed
With food
Optional
Duration
Safe long-term
Special Populations
Mild anxiety, sleep
Research & Studies
Search the literature now
We haven’t curated landmark studies for Passionfloweryet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Mechanism of Action
- • MAO inhibition
- • GABA-A modulation
- • Adenosine receptor activity
Evidence Quality
Evidence Grade B
Gentle, safe anxiolytic herb
Safety & Contraindications
Serious Warnings
- • None
Contraindications
- • None
Common Side Effects
- • Drowsiness
- • Dizziness
Pregnancy & Breastfeeding
Avoid in pregnancy
Liver & Kidney Notes
Safe
Interactions
💊 Medications
- • CNS depressants additive
- • Blood thinners
🧪 Supplements
- • Works with valerian, lemon balm
🍽️ Food & Alcohol
- • No interactions
Stacking & Synergies
Pairs Well With
Avoid Combining With
None
Best Goal Synergies
Gentle anxiety/sleep
Buying Guide
What to Look For
- • Quality extract
Standardization Markers
Flavonoid content
Adulteration risk
Low
Practical Notes
- • Very safe and gentle
- • Good for anxiety-related sleep issues
Tags
sleepanxietygentletraditionalanxiolyticsleep-supportrelaxationtraditional-herbalcns-support
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CBD Oil
Non-psychoactive cannabis compound for anxiety, pain, and sleep. Legal status varies.
Chamomile
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Honokiol
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Last reviewed: June 2026 by the Formulate Research Team. Sources cited above; methodology and scoring criteria published here.
Cite this page
Formulate Research Team. (2026, June). Passionflower — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/passionflower
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.