Also known as: Nicotinamide mononucleotide, β-NMN, β-Nicotinamide Mononucleotide, NMN/NR
Direct NAD+ precursor popularized by longevity research. Supports cellular repair and energy.
Different chemical forms vary in absorption, side effects, and best use cases. Higher bioavailability scores indicate better absorption.
Beta isomer — the biologically active form, stable when properly manufactured
💡 Best when produced as a stable crystalline form. Sublingual delivery may improve uptake.
📝 Look for ≥99% purity, third-party tested, and 'Beta-NMN' specified on label.
Bypasses GI degradation via mouth tissue or phospholipid encapsulation
💡 Higher than oral capsules — bypasses some first-pass metabolism.
📝 Worth the cost if NMN is a priority in your stack.
Plain oral NMN, the most common format
💡 Moderate — partially degraded in stomach acid; converted to NR before reaching cells.
📝 Effective for most people. 250-1000 mg/day typical.
Different precursor — NR is converted to NMN in the body
💡 Excellent oral bioavailability. Niagen® (branded NR) has strong human trial data.
📝 If new to NAD+ precursors, NR has more validated data. NMN is one step closer to NAD+.
Long-term use
Longevity-focused
We haven’t curated landmark studies for NMN (Nicotinamide Mononucleotide)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Popular NAD+ precursor
Limited data
Safe
In-depth guides covering NMN (Nicotinamide Mononucleotide) — protocols, comparisons, and use cases.
Other ingredients in the Longevity category.
Formulate Research Team. (2026, September). NMN (Nicotinamide Mononucleotide) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/nmn
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.