He Shou Wu (Fo-Ti)
Also known as: Polygonum multiflorum, Fo-Ti, Fleece flower root
Overview
Traditional Chinese longevity herb for hair, vitality, and jing essence. Contains stilbenes and anthraquinones. Requires proper preparation.
Frequently Asked About He Shou Wu (Fo-Ti)
How much He Shou Wu (Fo-Ti) should I take?
When is the best time to take He Shou Wu (Fo-Ti)?
Should I take He Shou Wu (Fo-Ti) with food?
Does He Shou Wu (Fo-Ti) interact with medications?
What does He Shou Wu (Fo-Ti) pair well with?
Who should not take He Shou Wu (Fo-Ti)?
What are the side effects of He Shou Wu (Fo-Ti)?
Dosage
Cycle use, monitor liver
Hair, longevity, TCM protocols
Research & Studies
We haven’t curated landmark studies for He Shou Wu (Fo-Ti)yet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Mechanism of Action
- • Contains stilbenes (similar to resveratrol)
- • Anthraquinone content
- • Traditional jing tonic
- • Hair and vitality support
Evidence Quality
Traditional use strong, some safety concerns with preparation
Safety & Contraindications
- • Liver toxicity reported, especially raw form
- • Use prepared form only
- • Liver disease
- • Pregnancy
- • GI upset
- • Diarrhea
Avoid
Hepatotoxicity risk - monitor liver function
Interactions
- • Hepatotoxic drugs
- • May affect drug metabolism
- • Used in TCM formulas
- • Avoid alcohol (liver)
Stacking & Synergies
Buying Guide
- • Prepared/processed form only
- • Reputable TCM source
- • MUST use prepared form - raw causes liver damage
- • Traditional preparation critical
- • Monitor liver function
More in Longevity
Other ingredients in the Longevity category.
Cite this page
Formulate Research Team. (2026, June). He Shou Wu (Fo-Ti) — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/he-shou-wu
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.