Also known as: CAG, TA-65 active compound, Astragaloside IV metabolite
Astragalus-derived compound that may activate telomerase. Expensive and experimental telomere-focused longevity supplement.
Long-term safety data limited
Telomere/longevity focused
We haven’t curated landmark studies for Cycloastragenolyet — one-click into the primary literature here. PubMed (RCTs) is usually the highest-signal starting point.
Telomerase activation shown in vitro, human evidence limited
Avoid
Limited data
Other ingredients in the Longevity category.
Formulate Research Team. (2026, September). Cycloastragenol — Evidence-Based Supplement Guide. Formulate Supplement Encyclopedia. https://app.formulate-health.app/learning/supplements/cycloastragenol
Educational content based on published research and our scoring methodology. Not medical advice — consult a qualified healthcare provider before starting, stopping, or changing supplements, especially if you take medications, are pregnant, or have a medical condition.