Add your supplements, foods, meals — and any medications you take — to see how they interact. Findings are grouped by severity: what to avoid, what needs care or timing, and what actually works better together.
High-dose vitamin E can increase bleeding risk with blood thinners.
Why: Mild antiplatelet effect at high doses.
→ Avoid high doses without prescriber guidance.
High-dose fish oil can add to a blood thinner's effect and increase bleeding risk.
Why: EPA/DHA reduce platelet aggregation.
→ Discuss high doses with your prescriber; watch for easy bruising/bleeding.
Potassium supplements with these drugs can cause dangerously high potassium.
Why: These drugs reduce potassium excretion.
→ Only supplement potassium under prescriber guidance with labs.
Vitamin D: Glucocorticoids (reduced vitamin D effectiveness)
Vitamin D: Anticonvulsants like phenytoin (increased vitamin D metabolism)
Vitamin D: Orlistat (reduced fat-soluble vitamin absorption)
Vitamin B1 (Thiamine): Loop diuretics deplete
Vitamin B2 (Riboflavin): None significant
Niacin (Vitamin B3): Statins (myopathy risk)
Niacin (Vitamin B3): Blood pressure meds
Vitamin B12 (Cobalamin): Metformin reduces absorption
Vitamin B12 (Cobalamin): PPIs reduce absorption
Selenium: May affect thyroid medication needs
Copper: Penicillamine, zinc, antacids reduce absorption
Chromium Picolinate: May enhance diabetes meds
Alpha-Lipoic Acid (ALA): Diabetes meds - enhance effect
CoQ10 (Ubiquinone/Ubiquinol): Statins deplete - always supplement
CoQ10 (Ubiquinone/Ubiquinol): Blood thinners - may reduce effect
Hawthorn Berry Extract: Digoxin (may enhance)
Hawthorn Berry Extract: Blood pressure meds (additive)
Milk Thistle (Silymarin): May affect CYP450 metabolism
Milk Thistle (Silymarin): Diabetes medications (may enhance)
Milk Thistle (Silymarin): Statins (may affect levels)
Fish Oil (EPA/DHA): Blood thinners additive
Fish Oil (EPA/DHA): BP meds may enhance
Magnesium can bind these drugs and reduce their absorption.
Why: Cation chelation in the gut.
→ Separate magnesium from these medications by 2–4 hours.
Calcium can bind these drugs and reduce their absorption.
Why: Cation chelation in the gut.
→ Separate calcium from these medications by 2–4 hours.
Vitamin E pairs well with CoQ10 (Ubiquinone/Ubiquinol).
Vitamin B1 (Thiamine) pairs well with Magnesium.
Vitamin B2 (Riboflavin) pairs well with Magnesium.
Vitamin B2 (Riboflavin) pairs well with CoQ10 (Ubiquinone/Ubiquinol).
Folate pairs well with Vitamin B12 (Cobalamin).
Chromium Picolinate pairs well with Alpha-Lipoic Acid (ALA).
CoQ10 (Ubiquinone/Ubiquinol) pairs well with Magnesium.
Hawthorn Berry Extract pairs well with CoQ10 (Ubiquinone/Ubiquinol).
Hawthorn Berry Extract pairs well with Magnesium.
Hawthorn Berry Extract pairs well with Fish Oil (EPA/DHA).
Curcumin pairs well with Fish Oil (EPA/DHA).
Fish Oil (EPA/DHA) pairs well with Vitamin D.
Fish Oil (EPA/DHA) pairs well with Vitamin E.
