Add your supplements, foods, meals — and any medications you take — to see how they interact. Findings are grouped by severity: what to avoid, what needs care or timing, and what actually works better together.
High-dose vitamin E can increase bleeding risk with blood thinners.
Why: Mild antiplatelet effect at high doses.
→ Avoid high doses without prescriber guidance.
Potassium supplements with these drugs can cause dangerously high potassium.
Why: These drugs reduce potassium excretion.
→ Only supplement potassium under prescriber guidance with labs.
Vitamin D: Glucocorticoids (reduced vitamin D effectiveness)
Vitamin D: Anticonvulsants like phenytoin (increased vitamin D metabolism)
Vitamin D: Orlistat (reduced fat-soluble vitamin absorption)
Vitamin B1 (Thiamine): Loop diuretics deplete
Vitamin B2 (Riboflavin): None significant
Niacin (Vitamin B3): Statins (myopathy risk)
Niacin (Vitamin B3): Blood pressure meds
Vitamin B12 (Cobalamin): Metformin reduces absorption
Vitamin B12 (Cobalamin): PPIs reduce absorption
Selenium: May affect thyroid medication needs
Copper: Penicillamine, zinc, antacids reduce absorption
Chromium Picolinate: May enhance diabetes meds
Alpha-Lipoic Acid (ALA): Diabetes meds - enhance effect
Hawthorn Berry Extract: Digoxin (may enhance)
Hawthorn Berry Extract: Blood pressure meds (additive)
Milk Thistle (Silymarin): May affect CYP450 metabolism
Milk Thistle (Silymarin): Diabetes medications (may enhance)
Milk Thistle (Silymarin): Statins (may affect levels)
Magnesium can bind these drugs and reduce their absorption.
Why: Cation chelation in the gut.
→ Separate magnesium from these medications by 2–4 hours.
Calcium can bind these drugs and reduce their absorption.
Why: Cation chelation in the gut.
→ Separate calcium from these medications by 2–4 hours.
Vitamin B1 (Thiamine) pairs well with Magnesium.
Vitamin B2 (Riboflavin) pairs well with Magnesium.
Folate pairs well with Vitamin B12 (Cobalamin).
Chromium Picolinate pairs well with Alpha-Lipoic Acid (ALA).
Hawthorn Berry Extract pairs well with Magnesium.
