Add your supplements, foods, meals — and any medications you take — to see how they interact. Findings are grouped by severity: what to avoid, what needs care or timing, and what actually works better together.
High-dose vitamin E can increase bleeding risk with blood thinners.
Why: Mild antiplatelet effect at high doses.
→ Avoid high doses without prescriber guidance.
Potassium supplements with these drugs can cause dangerously high potassium.
Why: These drugs reduce potassium excretion.
→ Only supplement potassium under prescriber guidance with labs.
Vitamin D: Glucocorticoids (reduced vitamin D effectiveness)
Vitamin D: Anticonvulsants like phenytoin (increased vitamin D metabolism)
Vitamin D: Orlistat (reduced fat-soluble vitamin absorption)
Vitamin B1 (Thiamine): Loop diuretics deplete
Vitamin B2 (Riboflavin): None significant
Niacin (Vitamin B3): Statins (myopathy risk)
Niacin (Vitamin B3): Blood pressure meds
Vitamin B12 (Cobalamin): Metformin reduces absorption
Vitamin B12 (Cobalamin): PPIs reduce absorption
Choline (Various Forms): May interact with anticholinergics
Selenium: May affect thyroid medication needs
Chromium Picolinate: May enhance diabetes meds
Inositol: Lithium (may reduce inositol)
Lycopene: May have additive antiplatelet effects with warfarin or antiplatelet drugs (rare, clinical significance unclear)
CoQ10 (Ubiquinone/Ubiquinol): Statins deplete - always supplement
CoQ10 (Ubiquinone/Ubiquinol): Blood thinners - may reduce effect
Alpha-Lipoic Acid (ALA): Diabetes meds - enhance effect
NAC (N-Acetyl Cysteine): Nitroglycerin - enhances
NAC (N-Acetyl Cysteine): Some chemo - consult oncologist
Milk Thistle (Silymarin): May affect CYP450 metabolism
Milk Thistle (Silymarin): Diabetes medications (may enhance)
Milk Thistle (Silymarin): Statins (may affect levels)
Artichoke: May affect CYP450 metabolism
Artichoke: Cholesterol medications (additive)
Glycine: Clozapine interaction theoretically
Chlorella: Warfarin (vitamin K content)
Vitamin E pairs well with CoQ10 (Ubiquinone/Ubiquinol).
Vitamin B2 (Riboflavin) pairs well with CoQ10 (Ubiquinone/Ubiquinol).
Folate pairs well with Vitamin B12 (Cobalamin).
Chromium Picolinate pairs well with Alpha-Lipoic Acid (ALA).
NAC (N-Acetyl Cysteine) pairs well with Vitamin C.
NAC (N-Acetyl Cysteine) pairs well with Selenium.
NAC (N-Acetyl Cysteine) pairs well with Glycine.
Milk Thistle (Silymarin) pairs well with NAC (N-Acetyl Cysteine).
Milk Thistle (Silymarin) pairs well with Artichoke.
Taurine pairs well with CoQ10 (Ubiquinone/Ubiquinol).
