Energy
Mitochondrial + cofactor support
Every cell makes its energy (ATP) by running glucose and fat through the mitochondria — and almost every step needs a vitamin cofactor. The B-complex (B1, B2, B3, B5) are the literal hand-off molecules of the Krebs cycle and electron transport chain; iron sits inside the cytochromes that shuttle electrons; magnesium stabilizes the ATP molecule itself; B12 keeps the whole system supplied with usable substrate. When these cofactors run low the machinery still turns, just slowly — felt as the kind of fatigue that doesn't improve with rest. This is the supply chain sitting underneath every other system on this list.
How your supplements + diet cover this system right now — the nutrients feeding it, where the gaps are, and your own lab readouts.
The load-bearing nutrients — if these are deficient, this system shows symptoms first. Click any to see daily targets, top food sources, and supplements that supply it.
Lab markers that report on this system’s health.
Save a lab session under My Journey → Biomarkers to see your own values for these.
Where the biochemistry happens for this system.
DNA methylation, homocysteine clearance, methyl-donor supply
Glutathione, SOD, catalase — quenching oxidative stress
Krebs cycle + electron transport — ATP production
Hydroxyapatite formation, osteoblast cofactors
T3/T4 synthesis from tyrosine + iodine; deiodinase cofactors
CYP450 phase I + glutathione/sulfation/glycine phase II
Insulin sensitivity, GLUT4 translocation, glycemic control
Cholesterol/triglyceride handling, β-oxidation of fatty acids
Cortisol synthesis, adrenal cofactor supply, calming neurochemistry
Systems that share a load-bearing nutrient with this one.